Neomycin Sulfate

Chemical Name: 2-Deoxy-4-O-(2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl)-D-streptamine sulfate

CAS Number: 1405-10-3

Neomycin sulfate is a broad-spectrum antibiotic belonging to the aminoglycoside group. It exhibits strong antimicrobial activity against gram-negative bacteria such as Escherichia coli, Klebsiella, and Pseudomonas aeruginosa, as well as gram-positive bacteria such as Staphylococcus aureus and Streptococcus pyogenes. It is mainly used for the treatment of gastrointestinal infections caused by sensitive gram-negative bacteria.

Neomycin sulfate works by binding to the bacterial ribosome and inhibiting protein synthesis, leading to bacterial death. It is effective against a wide range of bacteria due to its ability to penetrate the outer membrane of gram-negative bacteria.